Analysis of incomplete two-period crossover trials with SAS PROC MIXED
نویسنده
چکیده
Different methods for analysing normally distributed data from a simple two-period, two-treatment crossover trial with SAS/STAT are explored. Special emphasis is given to trials in which some data from one of the two periods are missing. The size and the power of the statistical tests are investigated by simulating data under various scenarios. To select the most suitable method for a particular trial the number and pattern of the available data and the covariance structure of the variables must be considered. The paper is rather application oriented and empirical in nature and touches on theory on few occasions only.
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